New Product Registrations

Active	Escitalopram
Strengths	5/10/20 mg
Originator	Cipralex®
Size of originator	R 100 million
Main indication	Depression
Private sector market size rand value [1USD = R 8.00]	R 264 million
Market	SSRI's
Critical success factors	First generic to market Originator is fifth leading product in South Africa by value

Active	Finasteride
Strengths	1 mg
Originator	Propecia®
Size of originator	R 6.4 million
Main indication	Prevent androgenetic hairloss
Private sector market size rand value [1USD = R 8.00]	R 8.9 million
Market	Hair Loss Preventatives
Critical success factors	First generic to market Priced at 70% less than originator Anticipate huge growth in market now that "cosmetic drug" extremely affordable

Active	Losartan
Strengths	25/50/100 mg
Originator	Cozaar®
Size of originator	R 15 million
Main indication	Hypertension
Private sector market size rand value [1USD = R 8.00]	R 109 million
Market	ARB's
Critical success factors	First molecule of ARB class to be genericised First to launch both 50 mg and 100 mg

Active	Efavirenz
Strengths	600 mg
Originator	Stocrin®
Size of originator	R 92 million
Main indication	HIV / AIDS
Private sector market size rand value [1USD = R 8.00]	R 94.4 million
Market	Efavirenz
Critical success factors	Now first line prescription option for HIV / AIDS FDA and WHO approved Huge tender opportunity

Active	Levofloxacin
Strengths	250/500/750 mg
Originator	Tavanic®
Size of originator	R 80 million
Main indication	Bacterial Infections
Private sector market size rand value [1USD = R 8.00]	R 252 million
Market	Fluoroquinolones
Critical success factors	First and only 750 mg launched in South Africa Strong reputation for fluoroquinolone antibiotics eg: Utin, Ciploxx

Active	Finasteride
Strengths	5 mg
Originator	Proscar®
Size of originator	R 2.7 million
Main indication	Benign Prostatic Hypertrophy
Private sector market size rand value [1USD = R 8.00]	R 48.8 million
Market	BPH Products
Critical success factors	Second generic in South Africa Nearly 70% less than originator

Active	Warfarin
Strengths	1/3/5 mg
Originator	Warfarin
Size of originator	R 13.4 million
Main indication	Prevent blood clots
Private sector market size rand value [1USD = R 8.00]	R 13.4 million
Market	Warfarin
Critical success factors	We are launching the first and only generic 5mg as well as only 1mg which will make dosing options much easier

Active	Topiramate
Strengths	25/100/200 mg
Originator	Topamax®
Size of originator	R 25 million
Main indication	Epilepsy
Private sector market size rand value [1USD = R 8.00]	R 264 million
Market	Antiepileptics
Critical success factors	Another new generation antiepileptic added to the already successful Epitec

Active	Lamivudine
Strengths	300 mg
Originator	Originator first to market
Size of originator	First to market
Main indication	HIV / AIDS
Private sector market size rand value [1USD = R 8.00]	R 122 million
Market	Lamivudine
Critical success factors	Allows once daily dosing (instead of twice daily) which should improve compliance Same pricing as twice daily dosing

® Registered Trademarks
Cipralex^® is a registered trademark of Lundbeck
Propecia^® is a registered trademark of MSD
Cozaar^® is a registered trademark of MSD
Stocrin^® is a registered trademark of MSD
Tavanic^® is a registered trademark of Sanofi-Aventis
Proscar^® is a registered trademark of MSD
Topamax^® is a registered trademark of Janssen-Cilag